McLean, Ian, authorSchwerdtfeger, Luke, authorWilson, Jessie, authorHenry, Charles, authorTobet, Stuart, author2017-11-132017-11-132017https://hdl.handle.net/10217/184835Currently, most in vitro experimental models of the intestine rely upon cell lines, and consequently, lack the diverse representation of cells present in vivo. Slices of intestine, removed from living organisms, offer a better representation of in vivo physiology. However, current techniques for maintaining intestinal tissue in vitro are not capable of recapitulating the in vivo environment. This project utilizes 3D printing and microfluidic principles to design a device that delivers differential flows of media across the two surfaces of intestinal tissue. The device will enable the investigation of complex biological questions that previous models have been unable to address.born digitalStudent workspostersengCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.microfluidictissue culturemicrobiomeText