Localization and Behavior of Nuclear Lamin Proteins
Nuclear size has been observed to be irregular in cancer cells, and as such can be used to phenotypically identify cancer cells and their stages. Many cancers have unusually large nuclei, and in certain cancers, nuclear size increases as the cancer becomes more aggressive. In order to fully understand the impact nuclear size has in cancer, and determine to what extent it is a cause or effect, we must understand how nuclear size is controlled. Although significant progress has been made over the past few years, many of the mechanisms and intricacies behind nuclear size regulation remain unknown. ...
(For more, see "View full record.")