Effect of Neonatal Iron Supplementation on Microglial Activation in Huntington's Disease Mice
Huntington's Disease (HD) is a neurodegenerative disorder that results from the atrophy of portions of the brain that control movement, cognition, and personality. Currently there is no therapeutic cure for HD. One change to the brain environment in HD affected individuals is neuroinflammation, this could drive HD progression, but the mechanism is not well understood. Microglial cells, the immune cells of the brain could be a main component of this neuroinflammation and can be activated by oxidative stress. The research team led by Dr. Fox has previously found that supplementation of neonatal ...
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