Development of 166Ho skin patch to treat skin diseases with 1 MW TRIGA reactor
Isotopes from the lanthanide series are suitable for intense localized radiotherapy of tumors and melanomas. [superscript 166]Ho is a promising radioisotope for use in medical radiotherapy due to its relatively short half-life of 26.8 hours and emission of high-energy [beta]-particles. [superscript 166]Ho can be produced in suitable quantities using the USGS 1 MW TRIGA reactor located at the Denver Federal Center. A prototype patch was created by RF sputtering holmium oxide onto Kapton foil. The prototype patch showed that [beta]-particles have good penetration and rapid fall-off in the photographic ...
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