Novel luminescent nanosensors and their applications in quantifying and monitoring analyte gradients in bacterial biofilms
Bacterial biofilms are complex, heterogeneous communities of bacteria encased in an extracellular matrix of polysaccharides, DNA, protein, and other biopolymers. Biofilms are ubiquitous across bacterial species and are believed to be the default mode of growth for many species. Opportunistic pathogens such as Pseudomonas aeruginosa form biofilm infections in the airways of cystic fibrosis patients and in wounds. Because of reasons such as this, investigating the ways different metabolites are utilized is crucial to our understanding, use, and control of these complex microbial communities. In ...
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