Applications of spatial frequency modulation for imaging in cell deformation cytometry
In this thesis, we develop two novel system architectures for the measurement of the flow position, size, and shape of red blood cells flowing in a microfluidic channel for the primary purpose of cell elasticity cytometry. The current state of the art relies upon the use of expensive high speed (of order 100 fps) CCD cameras to observe optically stretched red blood cell relaxing from a stretched state. This method also requires the use of computationally expensive edge finding techniques in order to convert the images into useful size information, which is then used to compute the cell elasticity. ...
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