Now showing items 1-10 of 10
Evaluation of intrinsic and extrinsic factors associated with injury rates and patterns among recreational skiers and snowboarders at a Colorado ski resort
Author(s):Pierpoint, Lauren Amanda Liscom
Over 10 million people participate in skiing and snowboarding in the United States (U.S.), including 500,000 Colorado residents. Accordingly, an estimated 600,000 patients with skiing- or snowboarding-related injuries are ...
Translational approaches to predicting tuberculosis risk: from administrative data to transcriptional biomarkers
Author(s):Walter, Nicholas David
Tuberculosis (TB) is an ongoing global public health crisis. In 2013, approximately 9 million people developed active TB and 1.5 million died. This dissertation addresses high-priority challenges in risk prediction, diagnosis ...
Exploring the etiologic role of omega-3 fatty acids in the pathogenesis of rheumatoid arthritis
Author(s):Gan, Ryan William
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint destruction and systemic inflammation, and follows a disease paradigm characterized by three stages of the disease, where first there is an ...
COPD mortality in Colorado: the role of environmental exposures, regionality and ethnicity
Author(s):Kinney, Gregory Loyd
Chronic Obstructive Pulmonary Disease (COPD) is a condition caused by damage to the airways and alveoli that results in loss of elasticity, increased inflammation, increased mucus production and alveolar wall damage. This ...
Age-related etiologic heterogeneity in the onset of islet autoimmunity
Author(s):Frederiksen, Brittni Noel
Type 1 diabetes (T1D) is preceded by a pre-clinical phase of islet autoimmunity (IA) where the insulin-producing beta-cells of the pancreas are destroyed and circulating autoantibodies can be detected. Autoantibodies can ...
Examining the relationship between obstructive sleep apnea, pulmonary abnormalities, and cardiovascular disease
Author(s):Black-Shinn, Jennifer Louise
Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) or Overlap syndrome has been shown to occur anywhere between 1-40% in population and clinic studies. Subjects with overlap syndrome are at ...
Associations of exposure to physical activity and smoking during pregnancy and offspring body composition: the healthy start study
Author(s):Harrod, Curtis Stuart
Our objective was to examine the associations of pregnancy physical activity and prenatal smoking with offspring mass [i.e. body mass, fat mass (FM), fat-free mass (FFM)]. We analyzed mother-offspring pairs participating ...
Human influenza A virus infections in rural communities in Indonesia: a small area spatial analysis
In Indonesia, although the number of human fatalities from avian influenza is the largest globally, human influenza A is not a priority. There have been no studies on influenza A's burden, its risk factors, and its ...
Incident myocardial infarction and all-cause mortality is predicted by coronary artery calcium in heavy smokers
Author(s):Duca, Lindsey Marie
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in the world. Since the signal event of cardiovascular disease is most often death due to myocardial infarction (MI), there has been a lot of ...
Thyroid nodules as related to absorbed dose from iodine-131 in a Ukrainian cohort following the Chernobyl accident
The Chernobyl accident in 1986 exposed thousands of people to various radioactive isotopes of iodine, particularly iodine-131 (I-131). In subsequent years after exposure, a large increase in thyroid cancer among those ...