Gut microbiome composition in individuals infected with HIV and high-risk men who have sex with men and the implications for chronic inflammation and metabolic co-morbidity
The gut microbiome has a vast ability to influence human health. The microbiome’s influence is of particular interest in people living with HIV. HIV infection targets and depletes gut immune cells resulting in a change of the immune environment in the gut. Because of the intimate cross-talk between the gut microbiome and the immune system, microbiome composition has the potential to alleviate or exacerbate HIV disease progression via immune influence. However, an investigation of the gut microbiome composition of HIV-positive people and individuals at high risk of infection showed that the ...
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