Role of the tumor microenvironment on the progression of lung cancer, The
Lung cancer is the leading cause of cancer-related deaths, with an overall 5-year survival rate of less than 18%. Interactions between cancer cells and the tumor microenvironment (TME) can affect tumor progression. The TME is composed of a multitude of different cell types that include innate immune cells: dendritic cells, macrophages, myeloid cells; adaptive immune cells: CD4+ T cells CD8+ T cells, and other cells: vascular cells, and endothelial cells. Herein, I explore the interactions between cancer cells and immune cells in the TME using multiple techniques including in vitro co-cultures, ...
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