Novel requirements of the synaptic transmembrane protein Csmd2 in neuronal maturation and structural plasticity
The development and function of neural circuits is dependent on the coordinated expression of molecules that control how neurons develop the dendritic arbor and postsynaptic dendritic spines. Dysregulation of critical factors driving the structural maturation of neurons is associated with deficits in higher cognitive abilities such as learning, memory, and awareness. Here, I present two studies that describe novel characteristics and requirements for the transmembrane protein Csmd2 in neuronal maturation. First, I provide data that the Csmd2 mRNA and protein are expressed in the developing and ...
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Gutierrez, Mark Anthony
Franco, Santos J.