Gene expression patterns of gammaherpesviruses
Gammaherpesviruses (γHVs) are lymphotropic oncogenic viruses which include the human pathogens Kaposi’s sarcoma associated herpesvirus (KSHV) and Epstein-Barr virus, as well as the murine model murine gammaherpesvirus 68 (MHV68). γHVs are associated with many severe malignancies especially in immune compromised populations such as organ transplant recipients, and patients with AIDS. Like all herpesviruses, gammaherpesviruses establish lifelong infection of their hosts and exhibit two major infection phases during their lifecycle: latency and a productive phase of infection termed lytic replication, ...
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van Dyk, Linda F.