Role of lipid mediators in preclinical rheumatoid arthritis, The
Rheumatoid arthritis (RA) is the most common form of systemic autoimmune inflammatory arthritis (IA) and is characterized by excessive chronic inflammation, which suggests a failure in the ability to control or resolve inflammation. The purpose of this dissertation is to elucidate the involvement of polyunsaturated fatty acid (PUFA)-derived lipid mediators during the preclinical period of RA. Specifically, we propose that lipid mediators with known roles in promoting and resolving inflammation are the way by which PUFAs impact incident IA risk. We conducted the first and largest study to ...
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Crume, Tessa; Norris, Jill
Embargo Expires: 06/22/2022