Role of plasmacytoid dendritic cells in anti-HCV immunity, The
Hepatitis C Virus (HCV) is a highly frequent blood borne pathogen worldwide. Approximately 80% of infected individuals will fail to clear the virus and develop a life-long persistent infection. Current therapies have increased the effective cure percentage to almost 70%. For many of these patients however, complete viral control comes after the virus has already done substantial damage to the liver, sometimes to the extent that a liver transplantation is required. Immunotherapy for HCV has not been fully studied nor is the immune response to the virus during early infection completely understood. ...
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Rosen, Hugo R.
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