Effects of nicotine on the neurobiology of selective attention in schizophrenia, The
Functional magnetic resonance imaging (fMRI) was used to examine the neuronal effects of nicotine during a selective attention task in patients with schizophrenia and healthy control subjects. Two analyses were performed. The first analysis examined the effects of acute nicotine (vs. placebo) administration on hippocampal and ventral parietal cortex (VPC) response during a go/no-go task in combination with environmental noise distractors. Significant drug X diagnosis interactions were observed in the hippocampus and VPC, driven by relatively increased response in patients under placebo conditions ...
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