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    • 2012 - 2016
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    MALDI-TOF mass spectrometry approach to biomarker discovery and validation, A

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    http://hdl.handle.net/10968/1737
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    A MALDI-TOF mass spectrometry approach to biomarker discovery and validation (2.800Mb)
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    Abstract
    Identifying biochemical markers for disease is a difficult endeavor. It requires methods that can quantify multiple components simultaneously, are high throughput, cost effective and deliver high precision and accuracy. In this thesis I explore the potential of matrix-assisted laser desorption/ionization (MALDI) for these applications. The approach developed for this study is a non-targeted MALDI based method to analyze biological tissues and fluids, and here I demonstrate its utility by way of the analysis of human tear fluid. I hypothesize that biomarker signatures of injury, wound repair ...
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    Author(s)
    Walsh, Ryan

    Advisor(s)
    Duncan, Mark W.; Bendiak, Brad

    Date Submitted
    2016
    Collections
    • 2012 - 2016
    • Theses and Dissertations - School of Medicine

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