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    • 2012 - 2016
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    microRNA control of neural progenitor maintenance and specification

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    http://hdl.handle.net/10968/1569
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    microRNA control of neural progenitor maintenance and specification (5.277Mb)
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    Abstract
    During neural development, progenitors both divide to expand the neural progenitor (NP) population and differentiate as neurons and glia. This balance of proliferation and differentiation is crucial to the proper development of the central nervous system (CNS). This balance appears to be regulated by multiple different mechanisms including apico-basal polarization by Partitioning defective proteins (Par) as well as Hedgehog signaling, which in addition to its role in dorso-ventral patterning also promotes progenitor proliferation. How both of these pathways are modulated at the end of neurogenesis ...
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    Author(s)
    Hudish, Laura Ioana

    Advisor(s)
    Appel, Bruce; Artinger, Kristin

    Rights Access
    Embargo Expires: 12/16/2016

    Date Submitted
    2016
    Collections
    • 2012 - 2016
    • Theses and Dissertations - School of Medicine

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