Collections in this community

Recent Submissions

  • Induction of antigen-specific tolerance in autoimmune diabetes using a hybrid insulin peptide 

    Author(s):Jamison, Braxton L.
    Date Issued:2020
    Format:born digital; doctoral dissertations
    T cells play a critical role in promoting the development of autoimmunity in Type 1 Diabetes (T1D) patients and the non-obese diabetic (NOD) mouse model. The CD4+ T cell clone BDC-2.5, originally isolated from a NOD mouse, ...
  • Role of microRNA-126 in lung microvascular endothelial cells 

    Author(s):Cao, Danting
    Date Issued:2020
    Format:born digital; doctoral dissertations
    Endothelial specific microRNA-126 (miR-126) is required for angiogenesis during development and repair of injured arterial vasculature in adult. Endothelial cells are a diverse group of cells with distinct molecular and ...
  • HIV TAT mediation of redox sensitive transcription factors in pulmonary vascular cells 

    Author(s):Simenauer, Ari M.
    Date Issued:2020
    Format:born digital; doctoral dissertations
    Chronic HIV infection in the era of anti-retroviral therapy is associated with dramatically increased risk of developing severe cardio-pulmonary disease. Common to these diseases are increased oxidative burden and chronic ...
  • Single cell analysis of biochemical phenotypes 

    Author(s):Richer, Amanda
    Date Issued:2020
    Format:born digital; doctoral dissertations
    Recent development of high throughput single cell methods has expanded our understanding of tissue heterogeneity, cell states, and developmental biology. Current single cell methods aim to understand cell function and ...
  • Interactions at the interface- mechanisms of capsular polysaccharide communication with the host in intestinal bacteroides 

    Author(s):Arnolds, Kathleen Louise
    Date Issued:2020
    Format:born digital; doctoral dissertations
    Millenia of co-evolution have shaped the relationships between humans and microbes, and signatures of these interactions can be found in the physiology of each. This thesis looks directly at host and microbial factors at ...
  • TGFβ-androgen receptor signaling axis affects anoikis resistance in triple negative breast cancer, A 

    Author(s):Rosas, Emmanuel
    Date Issued:2020
    Format:born digital; doctoral dissertations
    These studies were intended to identify a mechanism through which the TGFβ signaling pathway increases androgen receptor (AR) under anchorage independent conditions to promote anoikis resistance in triple-negative breast ...
  • Gut microbiome composition in individuals infected with HIV and high-risk men who have sex with men and the implications for chronic inflammation and metabolic co-morbidity 

    Author(s):Armstrong, Abigail Joy Streelman
    Date Issued:2020
    Format:born digital; doctoral dissertations
    The gut microbiome has a vast ability to influence human health. The microbiome’s influence is of particular interest in people living with HIV. HIV infection targets and depletes gut immune cells resulting in a change of ...
  • Deep artificial neural network models of neural encoding in vision and neurostimulation 

    Author(s):Christensen, Elijah
    Date Issued:2020
    Format:born digital; doctoral dissertations
    There is a significant need for more effective treatments for neurological and psychiatric diseases. Implantable neurostimulators are increasingly used as new therapeutic options for these diseases. This work will discuss ...
  • Chronic interleukin-1 exposure triggers selective expansion of CEBPA-deficient multipotent hematopoietic progenitors 

    Author(s):Higa, Kelly C.
    Date Issued:2020
    Format:born digital; doctoral dissertations
    The early events that drive hematologic disorders like clonal hematopoiesis, myelodysplastic syndrome, myeloproliferative neoplasm, and acute myeloid leukemia are not well understood. Most studies focus on the cell-intrinsic ...
  • Role of the tumor microenvironment on the progression of lung cancer, The 

    Author(s):Johnson, Amber Michelle
    Date Issued:2020
    Format:born digital; doctoral dissertations
    Lung cancer is the leading cause of cancer-related deaths, with an overall 5-year survival rate of less than 18%. Interactions between cancer cells and the tumor microenvironment (TME) can affect tumor progression. The TME ...
  • Role of poly/autoreactive B cells in the protective immune response, The 

    Author(s):Agazio, Amanda
    Date Issued:2020
    Format:born digital; doctoral dissertations
    Peripheral tolerance is essential for silencing weakly autoreactive B cells that have escaped central tolerance, but it is unclear why these potentially pathogenic B cells are retained rather than being eliminated entirely. ...
  • Mechanistic studies of GCN5 acetylation during craniofacial development and chondrocyte maturation 

    Author(s):Pezoa, Sofia Alia
    Date Issued:2020
    Format:born digital; doctoral dissertations
    Formation of the craniofacial skeleton involves the invasion of the migratory cranial neural crest (cNCC) into the pharyngeal arches, where they will terminally differentiate and contribute to the bone and cartilage that ...
  • William F. Vogt 

    Author(s):Division of Medical Photography. University of Colorado Medical Center; University of Colorado Anschutz Medical Campus. School of Medicine
    Date:1970-1980
    Format:Photograph
    University photograph of William F. Vogt.
  • Unknown person 

    Author(s):University of Colorado Anschutz Medical Campus. School of Medicine
    Date:1910-1920
    Format:Photograph
    Unknown person, possible medical faculty.
  • Mr. Dillon 

    Author(s):Division of Medical Photography. University of Colorado Medical Center; University of Colorado Anschutz Medical Campus. School of Medicine
    Date:1980-1990
    Format:Photograph
    University photograph of Mr. Dillon in the office.
  • Pharmacist and assistant 

    Author(s):University of Colorado Anschutz Medical Campus. School of Medicine
    Date:1920-1930
    Format:Photograph
    Pharmacist and assistant work in the lab.
  • Unknown person 

    Author(s):Division of Medical Photography. University of Colorado Medical Center; University of Colorado Anschutz Medical Campus. School of Medicine
    Date:1906
    Format:Photograph
    Unknown person, possible medical faculty.
  • Dr. Dane G. Prugh 

    Author(s):Division of Medical Photography. University of Colorado Medical Center; University of Colorado Anschutz Medical Campus. School of Medicine
    Date:1973-08-31
    Format:Photograph
    Dr. Dane Gaskill Prugh was director of affirmative action at the University of Colorado School of Medicine, and as President of the American Orthopsychiatric Association from 1968-1969.
  • Dr. James A. Philpott 

    Author(s):University of Colorado Anschutz Medical Campus. School of Medicine
    Date:1920-1930
    Format:Photograph
    Dr. James A. Philpott, class of 1912.
  • Graduation class 

    Author(s):University of Colorado Anschutz Medical Campus. School of Medicine
    Date:1880-1890
    Format:Photograph
    Class of fourteen unknown graduates.

View more