SINV induces oxidative stress in baby hamster kidney host cells
Alphaviruses belong to the Togaviridae family who has a species of virus known as the Sindbis virus. Sindbis virus shares characteristics with other alphaviruses that are currently causing worldwide infection and disease (i.e., Chikungunya virus, Ross River Virus and Western and Eastern Equine Encephalitis virus). Viruses are cellular parasites that invade and manipulate cellular energy pathways to support viral production. Oxidizing conditions are assumed to play a role in alphavirus replication. A modified Sindbis virus with a duplicated subgenomic promoter driving the expression of a fluorescent ...
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