CSU Home
    • Login
    View Item 
    •   Mountain Scholar Home
    • Colorado State University, Fort Collins
    • CSU Theses and Dissertations
    • 2000-2019 - CSU Theses and Dissertations
    • View Item
    •   Mountain Scholar Home
    • Colorado State University, Fort Collins
    • CSU Theses and Dissertations
    • 2000-2019 - CSU Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Autophagy modulation: role in anti-cancer therapy

    Thumbnail
    Citable Link(s)
    http://hdl.handle.net/10217/166885
    Download/View
    Barnard_colostate_0053A_12839.pdf (16.75Mb)
    View full record
    Altmetrics
    Abstract
    Autophagy is a conserved lysosomal degradation process characterized by cellular self-digestion. Autophagy results in turnover of the cytoplasm allowing for metabolic maintenance and organelle quality control, particularly during cell stress. These aspects of autophagy can facilitate tumor cell survival and resistance. As such, autophagy inhibition is being explored in clinical trials as a novel approach to chemosensitization. However, there are still a number of unresolved concerns in regards to the use of autophagy inhibition as a therapy. It is still unclear how autophagy functions in ...
    (For more, see "View full record.")
    Author(s)
    Barnard, Rebecca A.

    Advisor(s)
    Gustafson, Daniel L.

    Date Issued
    2015
    Format
    born digital; doctoral dissertations
    Collections
    • 2000-2019 - CSU Theses and Dissertations
    • Theses and Dissertations - Graduate Degree Program in Cell & Molecular Biology

    DSpace software   copyright © 2002-2016   DuraSpace
    Contact Us | Send Feedback
    Registered Repository
    RE3 Certified
    HTML Sitemap  

     

    Browse

    All of Mountain ScholarCommunities & CollectionsDatesAuthorsTitlesSubjectsThis CollectionDatesAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    DSpace software   copyright © 2002-2016   DuraSpace
    Contact Us | Send Feedback
    Registered Repository
    RE3 Certified
    HTML Sitemap