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    Novel extracellular products of Mycobacterium tuberculosis: composition, synthesis, and relevance to disease 

    Author(s):Obregón-Henao, Andrés
    Date Issued:2013
    Format:born digital; doctoral dissertations
    Mycobacterium tuberculosis (Mtb) is a bacterium causing great morbidity and mortality especially in developing countries. In order to identify possible areas of intervention to positively alter the history of the disease, ...
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    Characterizing the role of the HspX protein from Mycobacterium tuberculosis as a subunit vaccine candidate in the small animal model of tuberculosis 

    Author(s):Wieczorek, Agatha E.
    Date Issued:2011
    Format:born digital; masters theses
    Tuberculosis (TB) is a bacterial disease of the lung, caused by Mycobacterium tuberculosis, and currently remains an important human pathogen. The only vaccine against tuberculosis licensed for human use is a live, attenuated ...
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    Mycobacterium tuberculosis – mediated modulation of host macrophage metabolism in the granuloma microenvironment 

    Author(s):Kiran, Dilara
    Date Issued:2020
    Format:born digital; masters theses
    Mycobacterium tuberculosis (Mtb) is the leading cause of death by an infectious agent, and tuberculosis (TB) disease continues to be a prominent global health concern. Infection with Mtb incites granulomatous inflammation, ...
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    Comprehensive characterization of Mycobacterium tuberculosis strains after acquisition of isoniazid resistance 

    Author(s):Nieto Ramirez, Luisa Maria
    Date Issued:2016
    Format:born digital; doctoral dissertations
    Despite the global efforts to reduce tuberculosis (TB) rates, the emergence of drug resistant TB has not allowed effective control of this disease. In the last decade, there were roughly 10 million new TB cases per year ...
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    Characterization and quantification of urinary metabolic biomarkers for early response to anti-tuberculosis treatment 

    Author(s):Fitzgerald, Bryna
    Date Issued:2016
    Format:born digital; doctoral dissertations
    Development of new anti-tuberculosis (TB) therapies remains a major priority to combat this infectious disease and to prevent continued transmission of the causative agent Mycobacterium tuberculosis (Mtb). However, newly ...
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    Host directed therapy targeting M. tuberculosis infected macrophages 

    Author(s):Lakey, Natalie
    Date Issued:2016
    Format:born digital; masters theses
    With the rise of drug resistant strains of Mycobacterium tuberculosis (Mtb) and lags in antimicrobial drug development, it is imperative to explore alternative methods of treatment through host-directed adjunct therapies. ...
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    Bioinformatic identification and characterization of cytokinetic regulators in Mtb 

    Author(s):Crew, Rebecca M.
    Date Issued:2013
    Format:born digital; masters theses
    A fundamental lack of understanding of Mtb regulation during latent tuberculosis infections (LTBI), which comprises the vast majority of tuberculosis cases, has hindered global eradication efforts. To elucidate mechanisms ...
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    Exosomes: a potential novel source of biomarkers for tuberculosis 

    Author(s):Diaz, Gustavo
    Date Issued:2017
    Format:born digital; doctoral dissertations
    To view the abstract, please see the full text of the document.
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    Targeted computational analysis of the C3HEB/FEJ mouse model for drug efficacy testing 

    Author(s):Asay, Bryce Clifford
    Date Issued:2020
    Format:born digital; doctoral dissertations
    Efforts to develop effective and safe drugs for the treatment of tuberculosis (TB) require preclinical evaluation in animal models. Alongside efficacy testing of novel therapies, effects on pulmonary pathology and disease ...
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    Metformin: a tool to better understand T cell mediated protection against Mycobacterium tuberculosis 

    Author(s):Haugen Frenkel, Jessica D.
    Date Issued:2020
    Format:born digital; doctoral dissertations
    To view the abstract, please see the full text of the document.
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    AuthorAsay, Bryce Clifford (1)Crew, Rebecca M. (1)Diaz, Gustavo (1)Fitzgerald, Bryna (1)Fox, Amy (1)Haugen Frenkel, Jessica D. (1)Kiran, Dilara (1)Lakey, Natalie (1)Nieto Ramirez, Luisa Maria (1)Obregón-Henao, Andrés (1)... View MoreSubject
    tuberculosis (14)
    metabolism (4)biomarker (2)latency (2)proteomics (2)vaccine (2)2-deoxyglucose (1)adaptation (1)animal modeling (1)artificial intelligence (1)... View MoreDate Issued2020 - 2022 (7)2011 - 2019 (7)Has File(s)Yes (14)

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