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Identification and characterization of leprosy T cell antigens in the context of early diagnosis and CD1a restricted T cell activation
Author(s):Kim, Hee Jin
Date Issued:2011
Format:born digital; doctoral dissertations
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Development and evaluation of new leprosy skin test antigens as diagnostic tools
Author(s):Rivoire, Becky Louise
Date Issued:2012
Format:born digital; doctoral dissertations
An early diagnostic test for leprosy that is adequately sensitive and specific to identify infected individuals before the onset of clinical symptoms continues to be one of the greatest needs in the field. Preclinical ...
Characterization of Mycobacterium leprae diguanylate cyclases
Author(s):Rotcheewaphan, Suwatchareeporn
Date Issued:2016
Format:born digital; doctoral dissertations
Mycobacterium leprae is the causative agent of leprosy, which is still a major health problem in several developing countries. Management of leprosy has been challenging because of the long incubation period of the disease ...
Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos
Author(s):da Silva, Moises B.; Portela, Juliana M.; Li, Wei; Jackson, Mary; Gonzalez-Juarrero, Mercedes; Hidalgo, Andrea Sánchez; Belisle, John T.; Bouth, Raquel C.; Gobbo, Angélica R.; Barreto, Josafá G.; Minervino, Antonio H. H.; Cole, Stewart T.; Avanzi, Charlotte; Busso, Philippe; Frade, Marco A. C.; Geluk, Annemieke; Salgado, Claudio G.; Spencer, John S.
Date Issued:2018-06-28
Format:born digital; ariticles
Mycobacterium leprae (M. leprae) is a human pathogen and the causative agent for leprosy, a chronic disease characterized by lesions of the skin and peripheral nerve damage. Zoonotic transmission of M. leprae to humans by ...
Defining interactions between Mycobacterium leprae and Langerhans cells
Author(s):Fletcher, Darcy
Date Issued:2021
Format:born digital; doctoral dissertations
Leprosy is a chronic infection that affects the skin and peripheral nerves. Written accounts of the disease date back to at least 600 BC. Mycobacterium leprae, the causative agent of leprosy was first discovered by Dr. ...
Molecular epidemiology of leprosy: an update
Author(s):Avanzi, Charlotte; Singh, Pushpendra; Truman, Richard W; Suffys, Philip N
Date Issued:2020-12
Format:born digital; articles
Molecular epidemiology investigations are notoriously challenging in the leprosy field mainly because the inherent characteristics of the disease as well as its yet uncultivated causative agents, Mycobacterium leprae and ...