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Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos
Author(s):da Silva, Moises B.; Portela, Juliana M.; Li, Wei; Jackson, Mary; Gonzalez-Juarrero, Mercedes; Hidalgo, Andrea Sánchez; Belisle, John T.; Bouth, Raquel C.; Gobbo, Angélica R.; Barreto, Josafá G.; Minervino, Antonio H. H.; Cole, Stewart T.; Avanzi, Charlotte; Busso, Philippe; Frade, Marco A. C.; Geluk, Annemieke; Salgado, Claudio G.; Spencer, John S.
Date Issued:2018-06-28
Format:born digital; ariticles
Mycobacterium leprae (M. leprae) is a human pathogen and the causative agent for leprosy, a chronic disease characterized by lesions of the skin and peripheral nerve damage. Zoonotic transmission of M. leprae to humans by ...
MmpL3 interactome reveals a complex crosstalk between cell envelope biosynthesis and cell elongation and division in mycobacteria, The
Author(s):Belardinelli, Juan Manuel; Stevens, Casey M.; Li, Wei; Tan, Yong Zi; Jones, Victoria; Mancia, Filippo; Zgurskaya, Helen I.; Jackson, Mary
Date Issued:2019-07-24
Format:born digital; ariticles
Integral membrane transporters of the Mycobacterial Membrane Protein Large (MmpL) family and their interactome play important roles in the synthesis and export of mycobacterial outer membrane lipids. Despite the current ...
Therapeutic efficacy of antimalarial drugs targeting DosRS signaling in Mycobacterium abscessus
Author(s):Belardinelli, Juan Manuel; Verma, Deepshikha; Li, Wei; Avanzi, Charlotte; Wiersma, Crystal J.; Williams, John T.; Johnson, Benjamin K.; Zimmerman, Matthew; Whittel, Nicholas; Angala, Bhanupriya; Wang, Han; Jones, Victoria; Dartois, Veronique; de Moura, Vinicius C. N.; Gonzalez-Juarrero, Mercedes; Pearce, Camron; Schenkel, Alan R.; Malcolm, Kenneth C.; Nick, Jerry A.; Charman, Susan A.; Wells, Timothy N. C.; Podell, Brendan K.; Vennerstrom, Jonathan L.; Ordway, Diane J.; Abramovitch, Robert B.; Jackson, Mary
Date Issued:2022-02-23
Format:born digital; articles
A search for alternative Mycobacterium abscessus treatments led to our interest in the two-component regulator DosRS, which, in Mycobacterium tuberculosis, is required for the bacterium to establish a state of nonreplicating, ...