• Molecular regulation of glial inflammation in Parkinson's disease 

        Author(s):De Miranda, Briana R.
        Date Issued:2014
        Format:born digital; doctoral dissertations
        Parkinson's disease (PD) is the most prevalent movement disorder that affects adults, the primary pathology of which includes the loss of dopamine producing neurons from the substantia nigra (SN) and inflammatory activation ...
      • Use of fluorescent immunohistochemistry to investigate NF-κB involvement in brain pathologies 

        Author(s):Padmanabhan, N. Rachel
        Date Issued:2013
        Format:born digital; masters theses
        Nuclear Factor Kappa Beta (NF-κB) is a transcription factor ubiquitously expressed in mammalian cells and involved in a broad spectrum of physiological responses. In the central nervous system (CNS), NF-κB is responsible ...
      • Role of neuroinflammatory NF-KB signaling and glial crosstalk in neurodegeneration, The 

        Author(s):Kirkley, Kelly Sullivan
        Date Issued:2013
        Format:born digital; doctoral dissertations
        Neuroinflammation or inflammatory activation of astrocytes and microglia are considered pathological hallmarks and important mechanisms in debilitating neurodegenerative diseases. However, the signaling mechanisms underlying ...
      • Neuroinflammation and the two-hit hypothesis of Parkinson's disease 

        Author(s):Bantle, Collin M.
        Date Issued:2019
        Format:born digital; doctoral dissertations
        The ever-increasing prevalence of neurodegenerative diseases, Alzheimer's Disease (AD) and Parkinson's disease (PD), impose one the most significant medical and public health threats throughout the world. Characteristic ...