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Influence of adipose-derived mesenchymal stromal cells on osteosarcoma minimal residual disease
Author(s):Aanstoos-Ewen, Megan
Date Issued:2015
Format:born digital; doctoral dissertations
Introduction: Mesenchymal stromal cells (MSCs) have been shown to improve bone integration and healing in several preclinical studies and have therapeutic potential in limb salvage following massive bone loss due to tumor ...
Clinical importance of autophagy dependency and inhibition in cancer treatment
Author(s):Van Eaton, Kristen M.
Date Issued:2021
Format:born digital; doctoral dissertations
Autophagy, a lysosomal degradation recycling process, has a complex and context-dependent role in cancer. Certain cancers have been found to be inherently dependent on autophagy for survival regardless of the environment. ...