Browsing by Author "Carlson, Jonathan, advisor"
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Item Open Access Characterization of mosquito densonucleosis virus non-structural protein NS2(Colorado State University. Libraries, 2008) Azarkh, Yevgeniy "Eugene," author; Carlson, Jonathan, advisorMosquito densonucleosis viruses (or mosquito densoviruses) are insect parvoviruses that present practical interest as potential bio-insecticides and theoretical interest as a distinct parvoviral group with unique properties. Non-structural protein NS2 of the mosquito densonucleosis viruses is poorly characterized and bears no sequence similarity to NS2 proteins of other parvoviruses. It was hypothesized that mosquito densovirus NS2 is required for efficient viral propagation in cell cultures and during mosquito host infections, and that direct interactions between NS2 and other viral constituents are likely to play a role in NS2-mediated stages of viral life cycle.